Woman’s skin cells aged 30 years in trial, scientists claim

The research builds on the technology used to clone the sheep Dolly.

Scientists have been able to find a way to reverse the aging process in human skin. Thanks to groundbreaking research, a team of Cambridge scientists claim to have rejuvenated the skin cells of a 53-year-old woman by 30 years.

This is a longer reversal of the aging clock than any other previous study without damaging cells. A study detailing the method was published in eLife magazine.

The team told the BBC that it can do the same with other body tissues. Their ultimate goal is to develop treatments for age-related diseases, such as diabetes, heart disease and neurological diseases.

“This work has very exciting implications. Eventually, we may be able to identify genes that rejuvenate without reprogramming, and specifically target those that reduce the effects of aging,” said Professor Wolf Reik, group leader of the program of Epigenetics research. Sky News.

The findings are still in their infancy and if more research is carried out, the method could revolutionize regenerative medicines, the scientists said.

It is built on the technology used to clone the Dolly sheep over 25 years ago.

dolly the sheep

Researchers at the Roslin Institute in Scotland have cloned Dolly by developing a method that turns the mammary gland cell taken from a sheep into an embryo. The gland was taken from a six-year-old Finn Dorset sheep and an egg was taken from a Scottish Blackface sheep.

Dolly was born on July 5, 1996.

The technique aimed to create human embryonic stem cells, which could be grown in specific tissues, such as muscle, cartilage and nerve cells. These tissues could be used to replace old body parts.

The technology used by Cambridge scientists

It is the gradual decline in the ability of cells to function optimally that leads to tissue dysfunction and disease. Regenerative biology aims to repair these old cells.

The Cambridge team used the Maturational Phase Transient Reprogramming (MPTR) method, which overcomes the problem of cellular identity erasure, allowing researchers to find the balance between rejuvenating cells while retaining their specialized cellular function.

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