The next 10 years (between 2024) to witness a boom in the cell-free protein expression market at a 6% CAGR


The Cellless Protein Expression Market will experience a CAGR of 6%, reaching US $ 268.4 million between 2024. With medical IoT involving the use of portable monitors, devices and various integrated applications relating to healthcare needs, the vertical sector health is set to reach new heights in the next period. This is what the health care vertical would be in the next 10 years.

Persistence Market Research (PMR) Provides Key Insights on the Global Cellless Protein Expression Market in its upcoming report titled, “Cellless Protein Expression Market: Global Industry Analysis and Forecast, 2016-2024”. In terms of revenue, the global cell-free protein expression market is expected to register a 6.0% CAGR over the forecast period due to various factors, about which PMR offers detailed information and forecast.

Global Cellless Protein Expression Market Dynamics

The major factors fueling the demand for the cell-free protein expression market are the increasing outsourcing of R&D by pharmaceutical and biotechnology companies, declining R&D productivity, and falling patent sales resulting in high intensity. growing research in the pharmaceutical sector and increased spending on the development of biosimilars.

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Company Profiles

  • New England Biolabs
  • GeneCopoeia, Inc.
  • Takara Bio company
  • CellFree Sciences Co., Ltd.
  • Thermo Fisher Scientific Inc.
  • Promega Company
  • Bioneer Company
  • Biotech cube
  • biotechrabbit GmbH
  • Jena Bioscience GmbH

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The other factors driving the cell-free protein expression market are a growing demand for simple and efficient protein production methods, a contamination-free approach, and a growing focus on the production of mammalian cell-free lysates due to drug discovery.

One of the major bottlenecks in the cell-free protein expression market is the low volume of protein production in the process. This limitation makes cell-free protein expression unsuitable for large industrial applications and is generally preferred in small R&D processes. However, efforts are being made to overcome this constraint and make it a preferred expression system in an industrial environment.

Global Cellless Protein Expression Market Forecast

The market is segmented on the basis of product type, application, mode of expression, end users, and region. Based on the type of product, the market has been segmented into E. coli cell-free protein expression system, rabbit reticulocyte cell-free protein expression system, wheat germ cell-free protein expression system , protein expression system without cells of insect cells, mammalian cell -Free protein expression system, and consumables (labeling labels, vectors).

The segment of the mammalian cell-free protein expression system is expected to grow at the fastest CAGR during the forecast period, due to the increasing use of mammalian cell lysate in humanized proteomic and biological studies. The segment is expected to register a significant 6.0% CAGR during the forecast period.

The wheat germ cell-free protein expression system is also expected to witness a 5.8% CAGR over the forecast period. The growing demand for simpler, faster and more efficient protein production methods is driving the market for cell-free protein expression in research and development.

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The market has been segmented on the basis of major applications such as enzyme engineering, protein labeling, protein-protein interaction, and protein purification. The protein-protein interaction segment is expected to register the highest CAGR of 6.0% during the forecast period due to the increasing number of proteomic studies. The simple presentation of the cell-free protein expression system facilitates their integration into high throughput platforms for efficient biological and proteomic studies.

Cellless protein expression systems allow protein screening without requiring a gene cloning step, thus enabling accelerated process / product development pipelines, which presents an attractive opportunity for market players.

On the basis of end users, the market has been segmented into biotechnology companies, pharmaceutical companies, contract research organizations, and academic / research institutes. Academic / research institutes are expected to represent the highest market share during the forecast period, registering a 6.1% CAGR due to broad research applications in generating protein libraries for functional genomic studies, personalized drug development studies, and expression of viral-like particles, among many other applications.

This report assesses the trends, which are driving the growth of each segment on a global and regional level, and offers potential takeaways, which could prove to be of considerable use to biopharmaceutical manufacturing companies who wish to enter the market for the expression of proteins without cells.

North America and Europe are expected to dominate the cell-free protein expression market with maximum market share in 2016. North America and Europe collectively are expected to account for over 65% of the market share of total cell-free protein expression market in terms of value in 2016. Among emerging markets, Asia-Pacific is expected to post the highest CAGR of 6.1% during the forecast period, owing to increased research and development spending in the region.

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