Strong bone marrow regeneration potential a

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Credit: Mary Ann Liebert, Inc., publishers

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted on rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A. Click here to read the article now.

Blood concentrates such as platelet-forming fibrin (PRF) are used in clinical practice to promote tissue regeneration in the fields of dentistry, orthopedic surgery and plastic surgery. In the current study, Masako Fujioka-Kobayashifrom Nippon Dental University, Tokyo, Japan, and colleagues present a new type of solid bone marrow aspiration concentrate (sBMAC) material and show its potential for regeneration in gingival fibroblasts and osteoblasts in vitro compared to that of conventional FRP.

sBMAC induced significantly higher migratory potential than PRF obtained from arterial or venous blood and also demonstrated greater cell growth.

According to the researchers, “treatment with sBMAC resulted in greater cell migration, angiogenesis, collagen synthesis, and osteoblast differentiation potential than either Ar-PRF or Ve-PRF. Therefore, it has been suggested that sBMAC might be a new candidate to promote wound healing and bone regeneration.

“Koyanagi and his co-authors from Nippon Dental University have elegantly shown that solid bone marrow aspirations may be a promising therapeutic approach to promote wound healing, especially in bony contexts. This exciting work sheds light on the growing use of naturally occurring materials as the basis for new therapies,” says Creation of fabrics Co-editor in chief John P. Fisher, Ph.D.Fischell Family Distinguished Professor & Department Chair, and Director of the NIH Center for Engineering Complex Tissues at the University of Maryland.

About the journal
Creation of fabrics is an authoritative peer-reviewed journal published monthly online and in print in three parts: Part A, the flagship journal published 24 times a year; Part B: Reviews, published every two months, and Part C: Methods, published 12 times a year. Led by the co-editors Antonios G. Mikos, PhDProfessor Louis Calder at Rice University, Houston, TX, and John P. Fisher, Ph.D., Fischell Family Distinguished Professor & Department Chair, and Director of the NIH Center for Engineering Complex Tissues at the University of Maryland, the Journal brings together scientific and medical experts in the fields of biomedical engineering, materials science, molecular biology and cellular and genetics. engineering. Management of Creation of fabrics Part B (reviews) and part C (methods) are provided by Katja Schenke-Layland, PhDEberhard Karls University, Tübingen and John A. Jansen, DDS, PhD, Radboud University, respectively. Full tables of contents and sample issue can be viewed online at Creation of fabrics website. Creation of fabrics is the official journal of the Tissue Engineering & Regenerative Medicine International Society (TERMIS). Full tables of contents and sample issue can be viewed on the Creation of fabrics website.

About the editor
Mary Ann Liebert, Inc., publishers is known for creating authoritative, peer-reviewed journals in many promising areas of science and biomedical research. Its magazine specializing in biotechnology, GEN (Genetic Engineering and Biotechnology News), was the first in its field and is today the most widely read industry publication in the world. A complete list of the firm’s more than 100 journals, books and newsmagazines is available on the site Mary Ann Liebert, Inc., publishers website.


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